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7 March 2022 Enhancing OCT microstructural scattering parameter imaging with angular diversity
Taylor M. Cannon, Brett E. Bouma, Nestor Uribe-Patarroyo
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Proceedings Volume PC11948, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI; PC1194815 (2022) https://doi.org/10.1117/12.2613074
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
Measuring light scattering properties using OCT stands to enhance its ability to capture clinically-relevant microstructural details, but challenges remain in accurately relating these properties to underlying tissue architecture. In this work, we demonstrate the collection of depth-multiplexed data at diverse scattering angles with a glass annulus to facilitate correction of imaging system-based signal biases and identify multiply scattering areas in tissue. Based on our promising preliminary results from phantoms and healthy excised tissue samples, we hope our approach will enhance the accuracy of quantitative scattering parameter measurements, and help to realize their potential in offering detailed microstructural characterization of biological tissues.
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Taylor M. Cannon, Brett E. Bouma, and Nestor Uribe-Patarroyo "Enhancing OCT microstructural scattering parameter imaging with angular diversity", Proc. SPIE PC11948, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI, PC1194815 (7 March 2022); https://doi.org/10.1117/12.2613074
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KEYWORDS
Scattering
Optical coherence tomography
Light scattering
Multiple scattering
Scatter measurement
Tissues
Modulation
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