Multi-wavelength multi-distance diffuse correlation spectroscopy system for assessment of premature infants’ cerebral hemodynamics

Nikola Otic; John Sunwoo; Yujing Huang; Alyssa Martin; Mitchell B. Robinson; Bernhard Zimmermann; Stefan A. Carp; Maria A. Franceschini; Marco Renna

doi:10.1117/12.2649662

7 March 2023 Multi-wavelength multi-distance diffuse correlation spectroscopy system for assessment of premature infants’ cerebral hemodynamics

Nikola Otic, John Sunwoo, Yujing Huang, Alyssa Martin, Mitchell B. Robinson, Bernhard Zimmermann, Stefan A. Carp, Maria A. Franceschini, Marco Renna

Author Affiliations +

Proceedings Volume PC12376, Optical Tomography and Spectroscopy of Tissue XV; PC123760E (2023) https://doi.org/10.1117/12.2649662
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Infants born at an extremely low gestational age are at an increased risk of intraventricular hemorrhaging during the first three postnatal days. We have built a standalone easy-to-use multi-wavelength multi-distance diffuse correlation spectroscopy system, which utilizes three time-multiplexed long coherence lasers at 785, 808, and 853 nm, single photon detectors, and photon time-tagging electronics to simultaneously quantify cerebral blood flow, tissue optical properties, and blood oxygen saturation. The system has been designed specifically for use on preterm infants. The device shows good agreement with a commercially available NIRS-DCS system. We are currently monitoring preterm infants and will show results.

Conference Presentation

Citation Download Citation

Nikola Otic, John Sunwoo, Yujing Huang, Alyssa Martin, Mitchell B. Robinson, Bernhard Zimmermann, Stefan A. Carp, Maria A. Franceschini, and Marco Renna "Multi-wavelength multi-distance diffuse correlation spectroscopy system for assessment of premature infants’ cerebral hemodynamics", Proc. SPIE PC12376, Optical Tomography and Spectroscopy of Tissue XV, PC123760E (7 March 2023); https://doi.org/10.1117/12.2649662

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