Tissue structure characterization of biotissue phantom by use of the speckle-correlometric technique

A. A. Isaeva; E. A. Isaeva; D. A. Zimnyakov; A. V. Pantyukov; Y. V. Agapova; M. A. Macheyev

doi:10.1117/12.2267935

24 March 2017 Tissue structure characterization of biotissue phantom by use of the speckle-correlometric technique

A. A. Isaeva, E. A. Isaeva, D. A. Zimnyakov, A. V. Pantyukov, Y. V. Agapova, M. A. Macheyev

Proceedings Volume 10336, Saratov Fall Meeting 2016: Optical Technologies in Biophysics and Medicine XVIII; 1033618 (2017) https://doi.org/10.1117/12.2267935
Event: Saratov Fall Meeting 2016: Fourth International Symposium on Optics and Biophotonics, 2016, Saratov, Russian Federation

Abstract

Speckle correlometry gives the possibilities to visualize tissue scattering structure analyzing the correlation characteristics of speckle-modulated images. In this work, the inhomogeneous multiple scattering medium with the "dynamic" long inclusions was investigated like a blood vessels in living tissue. The scattering media is 0.28% weight fraction of gelatin dissolved in water and 1 gram per liter (gL^-1) and 100 mg per liter (gL^-1) of TiO₂ for optical scattering. The movement of fluid (distilled water) in the cylindrical hole with given radius simulate a blood motion in the vessel. It was shown the possibility to determinate the depth location of dynamic inhomogeneities inside a scattering medium.

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A. A. Isaeva, E. A. Isaeva, D. A. Zimnyakov, A. V. Pantyukov, Y. V. Agapova, and M. A. Macheyev "Tissue structure characterization of biotissue phantom by use of the speckle-correlometric technique", Proc. SPIE 10336, Saratov Fall Meeting 2016: Optical Technologies in Biophysics and Medicine XVIII, 1033618 (24 March 2017); https://doi.org/10.1117/12.2267935

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