There have been increasing interests in nonlinear optical imaging technology, especially in biomedical and material research fields, where higher spatial resolution, better sensitivity, deeper penetration and faster data acquisition are always desired. Most recent examples include fluorescence microscopy, coherent Raman and nonlinear wave mixing imaging. In this talk, we will present our recent progresses on deep tissue fluorescence super-resolution and non-labeling chiral sum frequency generation imaging by utilizing optical field engineering mechanism.
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