ultrasensitive spectroscopy based on photonic waveguides on Al2O3/SiO2 platform

Elham Heidari; Xiaochuan Xu; Naimei Tang; Farzad Mokhtari-Koushyar; Hamed Dalir; Ray T. Chen

doi:10.1117/12.2289151

20 February 2018 Ultrasensitive spectroscopy based on photonic waveguides on Al₂O₃/SiO₂ platform

Elham Heidari, Xiaochuan Xu, Naimei Tang, Farzad Mokhtari-Koushyar, Hamed Dalir, Ray T. Chen

Proceedings Volume 10501, Optical Diagnostics and Sensing XVIII: Toward Point-of-Care Diagnostics; 105011D (2018) https://doi.org/10.1117/12.2289151
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

Here a photonic waveguide on Al₂O₃/SiO₂ platform is proposed to cover the 240~320 nm wavelength-range, which is of paramount significance in protein and nuclei acid quantification. Our optical waveguide increases path-length and overlap integration for light-matter interaction with proteins. The proposed system detects one order less proteins concentration as low as 12.5 μg/ml compared with NanoDrop^TM that detects <125 μg/ml. Also, a linear absorbance change up to protein concentration of 7500 μg/ml is experimentally attained which is based on the Beer-Lambert-law.

Citation Download Citation

Elham Heidari, Xiaochuan Xu, Naimei Tang, Farzad Mokhtari-Koushyar, Hamed Dalir, and Ray T. Chen "Ultrasensitive spectroscopy based on photonic waveguides on Al₂O₃/SiO₂ platform", Proc. SPIE 10501, Optical Diagnostics and Sensing XVIII: Toward Point-of-Care Diagnostics, 105011D (20 February 2018); https://doi.org/10.1117/12.2289151

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