Comparison of breast tumor diameter by intraoperative photoacoustic screening, magnetic resonance imaging and pathology

Ivan Kosik; Muriel Brackstone; Anat Kornecki; Astrid Chamson-Reig; Philip Wong; Morteza Heydari Araghi; Jeff Carson

doi:10.1117/12.2509795

27 February 2019 Comparison of breast tumor diameter by intraoperative photoacoustic screening, magnetic resonance imaging and pathology

Ivan Kosik, Muriel Brackstone, Anat Kornecki, Astrid Chamson-Reig, Philip Wong, Morteza Heydari Araghi, Jeff Carson

Author Affiliations +

Proceedings Volume 10878, Photons Plus Ultrasound: Imaging and Sensing 2019; 108782K (2019) https://doi.org/10.1117/12.2509795
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Due to its superior molecular sensitivity, surgical management of breast cancer now often includes preoperative dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). Nevertheless, statistics indicate that, in practice, tumor size is frequently misestimated leading to incomplete resections, and consequently, repeat surgeries. Our group developed a surgical specimen assessment technique, called intraoperative photoacoustic screening (iPAS), based on photoacoustic tomography and with the capability to visualize whole breast tumors. The system was deployed at a breast surgical center and used to scan freshly excised breast tissue specimens belonging to 12 patients. This report compares breast cancer imaging performance by iPAS to that of DCE-MRI, and pathology.

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Citation Download Citation

Ivan Kosik, Muriel Brackstone, Anat Kornecki, Astrid Chamson-Reig, Philip Wong, Morteza Heydari Araghi, and Jeff Carson "Comparison of breast tumor diameter by intraoperative photoacoustic screening, magnetic resonance imaging and pathology", Proc. SPIE 10878, Photons Plus Ultrasound: Imaging and Sensing 2019, 108782K (27 February 2019); https://doi.org/10.1117/12.2509795

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