Laboratory-based x-ray phase contrast CT technology for clinical intra-operative specimen imaging

Lorenzo Massimi; Charlotte K. Hagen; Marco Endrizzi; Peter R. T. Munro; Glafkos Havariyoun; P. M. Sam Hawker; Bennie Smit; Alberto Astolfo; Oliver J. Larkin; Richard M. Waltham; Zoheb Shah; Stephen W. Duffy; Rachel L. Nelan; Anthony Peel; Tamara Suaris; J. Louise Jones; Ian G. Haig; Alessandro Olivo

doi:10.1117/12.2511770

1 March 2019 Laboratory-based x-ray phase contrast CT technology for clinical intra-operative specimen imaging

Lorenzo Massimi, Charlotte K. Hagen, Marco Endrizzi, Peter R. T. Munro, Glafkos Havariyoun, P. M. Sam Hawker, Bennie Smit, Alberto Astolfo, Oliver J. Larkin, Richard M. Waltham, Zoheb Shah, Stephen W. Duffy, Rachel L. Nelan, Anthony Peel, Tamara Suaris, J. Louise Jones, Ian G. Haig, Alessandro Olivo

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Proceedings Volume 10948, Medical Imaging 2019: Physics of Medical Imaging; 109481R (2019) https://doi.org/10.1117/12.2511770
Event: SPIE Medical Imaging, 2019, San Diego, California, United States

Abstract

The design of an X-ray phase contrast tomography system for intra-operative specimen imaging based on edge illumination is presented. The use of edge illumination makes possible working with large focus, polychromatic X-ray sources reducing acquisition times of tomography scans down to values compatible with clinical use, while maintaining phase sensitivity in a compact device. The results collected so far show that application of this technology to breast conservation surgery has great potential to reduce re-operations, thus saving additional costs for healthcare services and stress for patients.

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Lorenzo Massimi, Charlotte K. Hagen, Marco Endrizzi, Peter R. T. Munro, Glafkos Havariyoun, P. M. Sam Hawker, Bennie Smit, Alberto Astolfo, Oliver J. Larkin, Richard M. Waltham, Zoheb Shah, Stephen W. Duffy, Rachel L. Nelan, Anthony Peel, Tamara Suaris, J. Louise Jones, Ian G. Haig, and Alessandro Olivo "Laboratory-based x-ray phase contrast CT technology for clinical intra-operative specimen imaging ", Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 109481R (1 March 2019); https://doi.org/10.1117/12.2511770

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