Fitting a spectral model for component analysis in diffuse optical tomography

Giuseppe Di Sciacca; Edoardo Ferocino; Andrea Farina; Antonio Pifferi; Paola Taroni; Simon Arridge

doi:10.1117/12.2527119

11 July 2019 Fitting a spectral model for component analysis in diffuse optical tomography

Giuseppe Di Sciacca, Edoardo Ferocino, Andrea Farina, Antonio Pifferi, Paola Taroni, Simon Arridge

Proceedings Volume 11074, Diffuse Optical Spectroscopy and Imaging VII; 1107426 (2019) https://doi.org/10.1117/12.2527119
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

Time Domain Diffuse Optical Tomography (TD-DOT) at different wavelengths can be used to retrieve tissue reconstructing the components of a two-region system starting from self-normalized time-dependent measurements performed in reflectivity geometry over multiple wavelengths. The proposed method performs a fit of a limited number of tissues parameters providing a good quantification of the components’ concentrations by applying a FEM-based Diffusion approximation of the TD-DOT direct model.

Citation Download Citation

Giuseppe Di Sciacca, Edoardo Ferocino, Andrea Farina, Antonio Pifferi, Paola Taroni, and Simon Arridge "Fitting a spectral model for component analysis in diffuse optical tomography", Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 1107426 (11 July 2019); https://doi.org/10.1117/12.2527119

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