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9 March 2020 Prediction of tissue optical properties using Monte Carlo modeling of photon transport in turbid media and integrating spheres (Conference Presentation)
Patrick D. Cook, Joel N. Bixler, Robert J. Thomas, Edward A. Early
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Proceedings Volume 11238, Optical Interactions with Tissue and Cells XXXI; 112380P (2020) https://doi.org/10.1117/12.2542548
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
We present an extension to existing Monte Carlo photon transport methods to simulate integrating sphere experiments. This method uses a Monte Carlo approach to simulate photon paths in tissue and an analytical expression for the probability of a photon in an integrating sphere being re-incident on the tissue. Analytical models, previous works on Monte Carlo photon transport, and measurements of a synthetic tissue phantom validate this method. We present two approaches to back-calculate the optical properties of samples. Experimental and simulation uncertainties are propagated through both methods. Both back-calculation methods find the optical properties of a sample accurately and precisely.
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Patrick D. Cook, Joel N. Bixler, Robert J. Thomas, and Edward A. Early "Prediction of tissue optical properties using Monte Carlo modeling of photon transport in turbid media and integrating spheres (Conference Presentation)", Proc. SPIE 11238, Optical Interactions with Tissue and Cells XXXI, 112380P (9 March 2020); https://doi.org/10.1117/12.2542548
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KEYWORDS
Monte Carlo methods
Photon transport
Integrating spheres
Tissue optics
Optical properties
Optical spheres
Laser tissue interaction
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