Distortion matrix concept for deep imaging in optical coherence microscopy (Conference Presentation)

Alexandre Aubry; Amaury Badon; Victor Barolle; Kristina Irsch; Albert C. Boccara; Mathias Fink

doi:10.1117/12.2544828

11 March 2020 Distortion matrix concept for deep imaging in optical coherence microscopy (Conference Presentation)

Alexandre Aubry, Amaury Badon, Victor Barolle, Kristina Irsch, Albert C. Boccara, Mathias Fink

Author Affiliations +

Proceedings Volume 11248, Adaptive Optics and Wavefront Control for Biological Systems VI; 1124804 (2020) https://doi.org/10.1117/12.2544828
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

In optical imaging, light propagation is affected by the medium inhomogeneities. Adaptive optics has been employed to compensate for sample-induced aberrations but the field-of-view is often limited to a single isoplanatic patch. Here, we propose a non-invasive approach based on the distortion matrix concept. This matrix basically connects any focusing point with the distorted part of its wave-front in reflection. Its time-reversal and entropy analysis allows to correct for high-order aberrations over multiple isoplanatic areas. We demonstrate a Strehl ratio enhancement up to 2500 and a diffraction-limited resolution until a depth of ten scattering mean free paths through biological tissues.

Conference Presentation

Citation Download Citation

Alexandre Aubry, Amaury Badon, Victor Barolle, Kristina Irsch, Albert C. Boccara, and Mathias Fink "Distortion matrix concept for deep imaging in optical coherence microscopy (Conference Presentation)", Proc. SPIE 11248, Adaptive Optics and Wavefront Control for Biological Systems VI, 1124804 (11 March 2020); https://doi.org/10.1117/12.2544828

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