Experimental study of pointed sapphire needles for interstitial laser therapy

Irina N. Dolganova; Arsen K. Zotov; Irina A. Shikunova; Kirill I. Zaytsev; Polina V. Aleksandrova; Elena E. Mukhina; Vladimir N. Kurlov

doi:10.1117/12.2559988

9 April 2020 Experimental study of pointed sapphire needles for interstitial laser therapy

Irina N. Dolganova, Arsen K. Zotov, Irina A. Shikunova, Kirill I. Zaytsev, Polina V. Aleksandrova, Elena E. Mukhina, Vladimir N. Kurlov

Author Affiliations +

Proceedings Volume 11458, Saratov Fall Meeting 2019: Laser Physics, Photonic Technologies, and Molecular Modeling; 114580E (2020) https://doi.org/10.1117/12.2559988
Event: Saratov Fall Meeting 2019: VII International Symposium on Optics and Biophotonics, 2019, Saratov, Russian Federation

Abstract

In this paper, we study the examples of sapphire capillary needles for interstitial laser thermotherapy and photodynamic therapy. Such needles are fabricated by means of the Edge-defined Film-fed Growth (EFG) technology, so that they feature an as-grown optical quality. The optical fiber, which is used for delivering laser radiation to tissue, is placed inside the capillary channel in the needle's body. The channel is closed at the one side, therefore, the fiber is protected from the direct contact with biological tissue. The needle's tip form plays a significant role in the formation of the particular radiation pattern and the corresponding volume of treatment. Using a tissue phantom, we have experimentally studied the radiation distribution formed by sapphire needles with different tip angle. The results demonstrate rather smooth spatial distribution of light, confirming the high surface quality of the needles and the ability to control the amount of exposed tissue by changing the tip angle.

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Irina N. Dolganova, Arsen K. Zotov, Irina A. Shikunova, Kirill I. Zaytsev, Polina V. Aleksandrova, Elena E. Mukhina, and Vladimir N. Kurlov "Experimental study of pointed sapphire needles for interstitial laser therapy", Proc. SPIE 11458, Saratov Fall Meeting 2019: Laser Physics, Photonic Technologies, and Molecular Modeling, 114580E (9 April 2020); https://doi.org/10.1117/12.2559988

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