Electrode displacement elastography for differentiating metastatic liver cancer microwave ablation procedures

Robert M. Pohlman; James L. Hinshaw; Timothy J. Ziemlewicz; Meghan G Lubner; Shane A. Wells; Fred T. Lee Jr.; Marci L. Alexander; Kelly L. Wergin; Tomy Varghese

doi:10.1117/12.2580741

15 February 2021 Electrode displacement elastography for differentiating metastatic liver cancer microwave ablation procedures

Robert M. Pohlman, James L. Hinshaw, Timothy J. Ziemlewicz, Meghan G Lubner, Shane A. Wells, Fred T. Lee Jr., Marci L. Alexander, Kelly L. Wergin, Tomy Varghese

Author Affiliations +

Proceedings Volume 11595, Medical Imaging 2021: Physics of Medical Imaging; 1159550 (2021) https://doi.org/10.1117/12.2580741
Event: SPIE Medical Imaging, 2021, Online Only

Conference Poster

Abstract

Primary liver cancers and liver metastases are malignancies resulting in high mortality rates [1, 2]. As a treatment method, microwave ablation (MWA) presents with treatment success similar to surgical resection while significantly reducing morbidity and mortality for patients, requiring ablative margins of 0.5 – 1.0 cm verified using medical imaging. Unfortunately, traditional imaging modalities used namely, contrast enhanced computed tomography and B-mode ultrasound have limitations in providing visualization for validating MWA efficacy. Alternatively, electrode displacement elastography (EDE) has shown potential in visualizing MWA post ablation regions. However, EDE has not been used previously for comparing the pre and post ablation cross-sectional area measurements for ablative margin estimation and treatment of liver cancers. This work shows that EDE can achieve ablative margin estimation by comparing pre- and post- ablation EDE strain imaging for use in determining MWA efficacy.

Conference Presentation

Citation Download Citation

Robert M. Pohlman, James L. Hinshaw, Timothy J. Ziemlewicz, Meghan G Lubner, Shane A. Wells, Fred T. Lee Jr., Marci L. Alexander, Kelly L. Wergin, and Tomy Varghese "Electrode displacement elastography for differentiating metastatic liver cancer microwave ablation procedures", Proc. SPIE 11595, Medical Imaging 2021: Physics of Medical Imaging, 1159550 (15 February 2021); https://doi.org/10.1117/12.2580741

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