In this presentation I will describe our recent work to extend the spectral content of spatial frequency domain imaging (SFDI) to the short wave infrared (SWIR, 900-1300 nm). I will describe the unique instrumentation and methods needed for SWIR-SFDI measurements, and discuss the advantages and tradeoffs of imaging in the SWIR compared to the VIS and NIR. I will also present several preclinical and clinical application examples of SWIR-SFDI, including monitoring of edema, blood lipids, and spatial mapping of lipids in tumors.
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