Low-cost time-gated imager for intraoperative nerve identification

Mark T. Scimone; Youbo Zhao; Jason R. Gunn; Brian W. Pogue; Nicusor V. Iftimia

doi:10.1117/12.2582710

5 March 2021 Low-cost time-gated imager for intraoperative nerve identification

Mark T. Scimone, Youbo Zhao, Jason R. Gunn, Brian W. Pogue, Nicusor V. Iftimia

Proceedings Volume 11625, Molecular-Guided Surgery: Molecules, Devices, and Applications VII; 116250H (2021) https://doi.org/10.1117/12.2582710
Event: SPIE BiOS, 2021, Online Only

Abstract

Intraoperative nerve recognition is critical to avoid accidental transection. Fluorescence-guided surgery can aid in nerve identification. However, detection of weak nerve-specific fluorescence signal is susceptible to the interference from high-background bright lights. We present a time-gated imager designed with ease-of-use and cost effectiveness in mind. Using this technology, we demonstrate successful rejection of room-light background signal to visualize the murine sciatic nerve.

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Citation Download Citation

Mark T. Scimone, Youbo Zhao, Jason R. Gunn, Brian W. Pogue, and Nicusor V. Iftimia "Low-cost time-gated imager for intraoperative nerve identification", Proc. SPIE 11625, Molecular-Guided Surgery: Molecules, Devices, and Applications VII, 116250H (5 March 2021); https://doi.org/10.1117/12.2582710

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KEYWORDS

Nerve

Imaging systems

Luminescence

Cameras

CMOS cameras

Light emitting diodes

Light sources

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