Advanced electronic/optoelectronic systems that enable intimate integration with soft tissues of the brain, the spinal cord and the peripheral nerves will accelerate progress in neuroscience research; they will also serve as the foundations for new approaches in regenerative medicine and in the treatment of neurodegenerative disease. Specifically, capabilities for injecting miniaturized electronic elements, light sources, photodetectors, multiplexed sensors, programmable microfluidic networks and other components into precise locations of the deep brain or for softly laminating them onto the surfaces of peripheral nerves will open up unique and important opportunities in stimulating, inhibiting and monitoring neural circuit behaviors. This presentation describes concepts in materials science and assembly processes that underpin these types of technologies.
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