The culture and application of patient-derived tumour organoids

Xiaoyu Ren

doi:10.1117/12.2669049

24 March 2023 The culture and application of patient-derived tumour organoids

Xiaoyu Ren

Proceedings Volume 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022); 126113O (2023) https://doi.org/10.1117/12.2669049
Event: International Conference on Biological Engineering and Medical Science (ICBioMed2022), 2022, Oxford, United Kingdom

Abstract

In vitro cell culture plays an essential role in basic research and pre-clinical experiments on tumour tissue. However, as researchers study tumours more intensively, traditional in vitro cell culture models are inadequate for the study of tumours. Compared with traditional cell culture models, patient-derived organoid (PDO) can better reflect the pathogenesis and surrounding microenvironment of the original tumour in patients, providing researchers with a better model for studying tumour tissues. This paper focuses on the current state of the art of PDO, the application of PDO models in tumour research and the advantages of PDO models compare to traditional models, to provide a reference for subsequent research.

Citation Download Citation

Xiaoyu Ren "The culture and application of patient-derived tumour organoids", Proc. SPIE 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126113O (24 March 2023); https://doi.org/10.1117/12.2669049

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