Low-cost portable lens less digital holographic microscope for studying anemic RBCs

Aswathy Vijay; Ashwini Subhash Galande; Renu John

doi:10.1117/12.2670549

9 August 2023 Low-cost portable lens less digital holographic microscope for studying anemic RBCs

Aswathy Vijay, Ashwini Subhash Galande, Renu John

Proceedings Volume 12630, Advances in Microscopic Imaging IV; 1263016 (2023) https://doi.org/10.1117/12.2670549
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

Lensless digital holography is a low-cost imaging technique with promising applications in a resource deficit environment. It can be used for the diagnosis and analysis of RBCs. Modifications in their morphology and other physical parameters are indicative of several diseases. The sparsity constraint imposed by the twin image phenomenon in inline holography allows the implementation of compressive sensing based holographic reconstruction. It allows the estimation of parameters like size, thickness, volume, sphericity index etc. form the extracted phase information. In this work this approach is used to study RBC in healthy and anemic states.

Citation Download Citation

Aswathy Vijay, Ashwini Subhash Galande, and Renu John "Low-cost portable lens less digital holographic microscope for studying anemic RBCs", Proc. SPIE 12630, Advances in Microscopic Imaging IV, 1263016 (9 August 2023); https://doi.org/10.1117/12.2670549

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