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Near-infrared reflectance spectroscopy can serve as a complementary imaging tool that accurately provides endocardial substrates through optical mapping and improves the quality of ablation therapy. Optical indices were extracted from spectrum response, visualized similarity of blood and PBS maps interpolated from those indices were evaluated. Statistical analysis between blood and PBS optical indices were performed for each substrate type, and classification algorithms were developed using key features to classify pulmonary vein, lesion, and fibrosis with high accuracy. The results indicate NIRS mapping catheters can serve as a complementary imaging tool to the current EAM systems to improve treatment efficacy.
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Haiqiu Yang, Jonah A. Majumder, Ziyi Huang, Kenneth Laurita, Andrew M. Rollins, Christine P. Hendon, "High density optical substrate mapping of the left atrium with near infrared spectroscopy," Proc. SPIE 12819, Diagnostic and Therapeutic Applications of Light in Cardiology 2024, 128190S (13 March 2024); https://doi.org/10.1117/12.3002814