Investigating chemotherapy effects on peripheral nerve elasticity

Vsevolod Cheburkanov; Junwei Du; Mikhail Y. Berezin; Vladislav V. Yakovlev

doi:10.1117/12.3003568

12 March 2024 Investigating chemotherapy effects on peripheral nerve elasticity

Vsevolod Cheburkanov, Junwei Du, Mikhail Y. Berezin, Vladislav V. Yakovlev

Proceedings Volume 12821, Visualizing and Quantifying Drug Distribution in Tissue VIII; 1282109 (2024) https://doi.org/10.1117/12.3003568
Event: SPIE BiOS, 2024, San Francisco, California, United States

Conference Poster

Abstract

Chemotherapy is one of the treatment methods aimed at killing cancer cells and hindering their metastasis. However, chemotherapy is known to induce multiple adverse side-effects. One of them is peripheral neuropathy, which causes significant discomfort to the cancer patient. It is hypothesized that neuropathy is directly linked to peripheral nerve damage or elasticity change. In this study we have attempted to use Brillouin spectroscopy to evaluate nerve elasticity changes and correlate them to the effects of chemotherapy.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Vsevolod Cheburkanov, Junwei Du, Mikhail Y. Berezin, and Vladislav V. Yakovlev "Investigating chemotherapy effects on peripheral nerve elasticity", Proc. SPIE 12821, Visualizing and Quantifying Drug Distribution in Tissue VIII, 1282109 (12 March 2024); https://doi.org/10.1117/12.3003568

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