A robust vessel-labeling pipeline with high tissue clearing compatibility for 3D mapping of vascular networks

Yating Deng; Jingtan Zhu; Xiaomei Liu; Tingting Yu; Dan Zhu

doi:10.1117/12.3036828

20 November 2024 A robust vessel-labeling pipeline with high tissue clearing compatibility for 3D mapping of vascular networks

Yating Deng, Jingtan Zhu, Xiaomei Liu, Tingting Yu, Dan Zhu

Author Affiliations +

Proceedings Volume 13242, Optics in Health Care and Biomedical Optics XIV; 132422A (2024) https://doi.org/10.1117/12.3036828
Event: SPIE/COS Photonics Asia, 2024, Nantong, Jiangsu, China

Conference Poster

Abstract

Using vessel-labeling, tissue-clearing, and light-sheet imaging improves vascular mapping and disorder analysis. However, some labeling methods compromise efficiency and compatibility, reducing image quality. We present Ultralabel, a superior vessel-labeling method employing a unique hydrogel dye. Ultralabel outperforms others, offering accurate vascular mapping, multi-color labeling, and reliable, user-friendly 3D vascular network visualization for biomedical uses.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Yating Deng, Jingtan Zhu, Xiaomei Liu, Tingting Yu, and Dan Zhu "A robust vessel-labeling pipeline with high tissue clearing compatibility for 3D mapping of vascular networks", Proc. SPIE 13242, Optics in Health Care and Biomedical Optics XIV, 132422A (20 November 2024); https://doi.org/10.1117/12.3036828

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