Analysis of kinetic rate modeling of thermal damage in laser-irradiated tissue

Sohi Rastegar; Tami N. Fink

doi:10.1117/12.44114

1 June 1991 Analysis of kinetic rate modeling of thermal damage in laser-irradiated tissue

Sohi Rastegar, Tami N. Fink

Proceedings Volume 1427, Laser-Tissue Interaction II; (1991) https://doi.org/10.1117/12.44114
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

Theoretical modeling of the thermal and optical processes involved in the interaction of laser light with tissue has progressed both qualitatively and quantitatively as a tool for understanding laser coagulation and ablation. Optimal procedure and dosimetry prescription for laser irradiation of tissue in various applications requires a knowledge of the thermal damage process in tissue and its dynamic behavior. Previous work in the area of thermal damage modeling date back to the work of Henriques (1947) on pig skin. Agah et al. (1987) have evaluated damage coefficients for human vascular tissue. Interesting work on quantitative histology is in progress by Thomsen et al. (1989) in which thermal damage coefficients are correlated to birefringent microscopic observations. A study of the dynamics of thermal damage and ablation indicate the presence and variation of damage in different tissues even before the onset of the ablative process (Rastegar, et al. 1988). In the present study, using a kinetic rate model for thermal damage, the behavior of the damage model has been analyzed to determine sensitivities of tissue parameters, effects of temperature dependence, and possibility of predictions based on isotherm propagation.

Citation Download Citation

Sohi Rastegar and Tami N. Fink "Analysis of kinetic rate modeling of thermal damage in laser-irradiated tissue", Proc. SPIE 1427, Laser-Tissue Interaction II, (1 June 1991); https://doi.org/10.1117/12.44114

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Laser tissue interaction

Tissues

Thermal modeling

Injuries

Scattering

Skin

Laser scattering

Show All Keywords

Keywords/Phrases

Search In:

Publication Years