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1 June 1991 Indirect spectroscopic detection of singlet oxygen during photodynamic therapy
Bruce J. Tromberg, Tatiana B. Dvornikov, Michael W. Berns
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Proceedings Volume 1427, Laser-Tissue Interaction II; (1991) https://doi.org/10.1117/12.44091
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States
Abstract
Chemiluminescence (CL) and optical upconversion (OU) are used to measure photosensitizer singlet oxygen production indirectly. Both methods produce light that is blue-shifted relative to the normal photosensitizing wavelength. The emission intensity is proportional to the concentration of singlet oxygen generated and is the result of either decomposition (CL) or energy transfer (OU) processes occurring inside a thin polymer film. Techniques for fabrication and characterization of CL and OU polymer films are discussed.
© (1991) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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Bruce J. Tromberg, Tatiana B. Dvornikov, and Michael W. Berns "Indirect spectroscopic detection of singlet oxygen during photodynamic therapy", Proc. SPIE 1427, Laser-Tissue Interaction II, (1 June 1991); https://doi.org/10.1117/12.44091
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KEYWORDS
Oxygen
Upconversion
Photodynamic therapy
Chemiluminescence
Fiber optics sensors
Laser tissue interaction
Absorption
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