Time-resolved transillumination for medical diagnostics

Roger Berg; Stefan Andersson-Engels; Olof Jarlman M.D.; Sune Svanberg

doi:10.1117/12.44183

1 May 1991 Time-resolved transillumination for medical diagnostics

Roger Berg, Stefan Andersson-Engels, Olof Jarlman M.D., Sune Svanberg

Proceedings Volume 1431, Time-Resolved Spectroscopy and Imaging of Tissues; (1991) https://doi.org/10.1117/12.44183
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

We demonstrate a time-gated technique to reduce the effect of light scattering when transilluminating turbid media such as tissue. The concept is based on transillumination with picosecond laser pulses and time-resolved detection. By detecting only the photons with the shortest travelling time, and thus the least scattered photons, the contrast can be enhanced. Measurements on a tissue phantom as well as breast tissue in vitro are presented. It is demonstrated that differences in scattering properties may be more pronounced than differences in absorption properties when demarcating tumor from normal tissue.

Citation Download Citation

Roger Berg, Stefan Andersson-Engels, Olof Jarlman M.D., and Sune Svanberg "Time-resolved transillumination for medical diagnostics", Proc. SPIE 1431, Time-Resolved Spectroscopy and Imaging of Tissues, (1 May 1991); https://doi.org/10.1117/12.44183

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