Fluorescence detection of MSH-receptors in melanoma as a target of hormone-directed photosensitation in PDT

Susanne Roehrs; Joerg G. Moser; Yoram Salomon

doi:10.1117/12.199162

12 January 1995 Fluorescence detection of MSH-receptors in melanoma as a target of hormone-directed photosensitation in PDT

Susanne Roehrs, Joerg G. Moser, Yoram Salomon

Author Affiliations +

Proceedings Volume 2325, Photodynamic Therapy of Cancer II; (1995) https://doi.org/10.1117/12.199162
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

MSH receptors are one of the possible targets to specifically attack melanoma cells by photodynamically active agents bound to melanotropic hormones. To attack effectively metastatic melanoma the presence of the hormone receptor has to be proven in metastases. Radioactive labeling of melanotropic hormones allows us to check for the presence of intact receptors. We tried to develop a non-radioactive immunological method as a first step to work out therapeutic strategies to attach photodynamically active porphyrins to the surface of melanoma cells.

Citation Download Citation

Susanne Roehrs, Joerg G. Moser, and Yoram Salomon "Fluorescence detection of MSH-receptors in melanoma as a target of hormone-directed photosensitation in PDT", Proc. SPIE 2325, Photodynamic Therapy of Cancer II, (12 January 1995); https://doi.org/10.1117/12.199162

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available