Paper
9 April 1999 Analysis of pharmaceutical materials through the use of FT-Raman microprobe imaging
Christiane Rodriguez
Author Affiliations +
Proceedings Volume 3608, Biomedical Applications of Raman Spectroscopy; (1999) https://doi.org/10.1117/12.345412
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States
Abstract
The characterization of pharmaceutical solids has always ben a concern for the pharmaceutical scientist, whether it be a formulator, analytical chemist or process chemist. Traditionally, characterization meant chemical purity, but today a more comprehensive characterization is crucial for a safe and consistent pharmaceutical product. Typically, FTIR and FT-Raman are the vibrational techniques used to physical characterize solids. Recent advances in imaging technology have made FT-Raman microscopy another powerful tool for obtaining information of pharmaceutical products. This advance has made it possible to not only obtain chemical information, but gives the ability to spatially resolve the obtained information. Descriptions of various experimental procedures for analyzing formulated tablets as well as other materials of pharmaceutical interest using imaging techniques will be given.
© (1999) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Christiane Rodriguez "Analysis of pharmaceutical materials through the use of FT-Raman microprobe imaging", Proc. SPIE 3608, Biomedical Applications of Raman Spectroscopy, (9 April 1999); https://doi.org/10.1117/12.345412
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KEYWORDS
Tablets

Chemical analysis

Raman spectroscopy

Luminescence

Solids

FT-IR spectroscopy

Microscopes

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