In vivo observations of cytochrome P4501A isozyme reaction in liver of living rats by using fiber-optic sensor

Issei Sasaki

doi:10.1117/12.2302130

1 September 1999 In vivo observations of cytochrome P4501A isozyme reaction in liver of living rats by using fiber-optic sensor

Issei Sasaki

Author Affiliations +

Proceedings Volume 3746, 13th International Conference on Optical Fiber Sensors; 37463W (1999) https://doi.org/10.1117/12.2302130
Event: 13th International Conference on Optical Fiber Sensors, 1999, Kyongju, Korea, Republic of

Abstract

This paper reports on in vivo observations of enzymatic reaction in living rats by employing a fiber-optic sensor. O-dealkylation of ethoxyresorufin to resorufin due to cytochrome P450 1A isozyme is successfully detected by observing fluorescent emission from resorufin through optical fibers.

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Issei Sasaki "In vivo observations of cytochrome P4501A isozyme reaction in liver of living rats by using fiber-optic sensor", Proc. SPIE 3746, 13th International Conference on Optical Fiber Sensors, 37463W (1 September 1999); https://doi.org/10.1117/12.2302130

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