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The paper reports that penicillin-producing strains and lovastatin-producing strains were irradiated by UV and subsequently by laser (632.8 nm), and the reparation rate reached 297% and 264%. High-yield mutant was selected with improved potency of 24.5% and 30%, respectively; Gibberellin producing strains were treated with chemical agent LiCl, and then irradiated with 632.8 nm laser. One mutant with 189.6% increased potency was obtained. The experimental results indicated that using laser irradiation after UV or chemical agent mutation was a new useful method in breeding high-yield strains.
Yansheng Zhao,Canpeng Xiao,Hailun Qian,Baoliang Su,Yujun Hu, andJianhui Deng
"Repair effects of laser on mutants of filamentous fungi", Proc. SPIE 3863, 1999 International Conference on Biomedical Optics, (17 September 1999); https://doi.org/10.1117/12.364430
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Yansheng Zhao, Canpeng Xiao, Hailun Qian, Baoliang Su, Yujun Hu, Jianhui Deng, "Repair effects of laser on mutants of filamentous fungi," Proc. SPIE 3863, 1999 International Conference on Biomedical Optics, (17 September 1999); https://doi.org/10.1117/12.364430