Normalization and error estimation for biomedical expression patterns

Stanley D. Luck

doi:10.1117/12.427984

4 June 2001 Normalization and error estimation for biomedical expression patterns

Stanley D. Luck

Proceedings Volume 4266, Microarrays: Optical Technologies and Informatics; (2001) https://doi.org/10.1117/12.427984
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

We describe methods for the analysis expression patterns based on a vector representation for intensities. Normalization for multiple experiments is iterative and is obtained by identifying a vector that optimally correlates expression patterns. Error estimates for intensities are obtained by analyzing deviations in expression relative to the correlation vector. A normalization method for applying corrections from spiked, two-color fluorescence measurements is also described.

Citation Download Citation

Stanley D. Luck "Normalization and error estimation for biomedical expression patterns", Proc. SPIE 4266, Microarrays: Optical Technologies and Informatics, (4 June 2001); https://doi.org/10.1117/12.427984

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available