Robust registration method for interventional MRI-guided thermal ablation of prostate cancer

Baowei Fei; Andrew Wheaton; Zhenghong Lee; Kenichi Nagano; Jeffrey L. Duerk; David L. Wilson

doi:10.1117/12.428092

28 May 2001 Robust registration method for interventional MRI-guided thermal ablation of prostate cancer

Baowei Fei, Andrew Wheaton, Zhenghong Lee, Kenichi Nagano, Jeffrey L. Duerk, David L. Wilson

Proceedings Volume 4319, Medical Imaging 2001: Visualization, Display, and Image-Guided Procedures; (2001) https://doi.org/10.1117/12.428092
Event: Medical Imaging 2001, 2001, San Diego, CA, United States

Abstract

We are investigating methods to register live-time interventional magnetic resonance imaging (iMRI) slice images with a previously obtained, high resolution MRI image volume. The immediate application is for iMRI-guided treatments of prostate cancer. We created and evaluated a slice-to-volume mutual information registration algorithm for MR images with special features to improve robustness. Features included a multi-resolution approach and automatic restarting to avoid local minima. We acquired 3D volume images from a 1.5 T MRI system and simulated iMRI images. To assess the quality of registration, we calculated 3D displacement on a voxel-by-voxel basis over a volume of interest between slice-to-volume registration and volume-to- volume registrations that were previously shown to be quite accurate. More than 500 registration experiments were performed on MR images of volunteers. The slice-to-volume registration algorithm was very robust for transverse images covering the prostate. A 100% success rate was achieved with an acceptance criterion of <1.0 mm displacement error over the prostate. Our automatic slice-to-volume mutual information registration algorithm is robust and probably sufficiently accurate to aid in the application of iMRI- guided thermal ablation of prostate cancer.

Citation Download Citation

Baowei Fei, Andrew Wheaton, Zhenghong Lee, Kenichi Nagano, Jeffrey L. Duerk, and David L. Wilson "Robust registration method for interventional MRI-guided thermal ablation of prostate cancer", Proc. SPIE 4319, Medical Imaging 2001: Visualization, Display, and Image-Guided Procedures, (28 May 2001); https://doi.org/10.1117/12.428092

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