Multimodal information integration and visualization: optical imaging and MRI

Fred S. Azar; Mazen ElBawab; Ali Khamene; Kijoon Lee; Regine Choe; Alper Corlu; Soren D. Konecky; Arjun G. Yodh; Frank Sauer

doi:10.1117/12.638976

22 November 2005 Multimodal information integration and visualization: optical imaging and MRI

Fred S. Azar, Mazen ElBawab, Ali Khamene, Kijoon Lee, Regine Choe, Alper Corlu, Soren D. Konecky, Arjun G. Yodh, Frank Sauer

Author Affiliations +

Proceedings Volume 6009, Optical Methods in Drug Discovery and Development; 60090E (2005) https://doi.org/10.1117/12.638976
Event: Optics East 2005, 2005, Boston, MA, United States

Abstract

We have developed a software platform for multimodal integration and visualization of diffuse optical tomography (DOT) and magnetic resonance imaging (MRI) of breast cancer. The image visualization platform allows multimodality 3D image visualization and manipulation of datasets, such as a variety of 3D rendering technique, and the ability to simultaneously control multiple fields of view. This platform enables quantitative and qualitative analysis of structural and functional diagnostic data, using both conventional & molecular imaging. The functional parameters, together with morphological parameters from MR can be suitably combined and correlated to the absolute diagnosis from histopathology. Fusion of the multimodal datasets will eventually lead to a significant improvement in the sensitivity and specificity of breast cancer detection. Fusion may also allow a priori structural information derived from MRI to be incorporated into the reconstruction of diffuse optical tomography images. We will present the early results of image visualization and registration on multimodal breast cancer data, DOT and MRI.

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Fred S. Azar, Mazen ElBawab, Ali Khamene, Kijoon Lee, Regine Choe, Alper Corlu, Soren D. Konecky, Arjun G. Yodh, and Frank Sauer "Multimodal information integration and visualization: optical imaging and MRI", Proc. SPIE 6009, Optical Methods in Drug Discovery and Development, 60090E (22 November 2005); https://doi.org/10.1117/12.638976

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