Development of ultrasound technique to detect and characterize laser-induced microbubbles

Andrei B. Karpiouk; Frederic Bourgeois; Salavat R. Aglyamov; Adela Ben-Yakar; Stanislav Y. Emelianov

doi:10.1117/12.701874

6 February 2007 Development of ultrasound technique to detect and characterize laser-induced microbubbles

Andrei B. Karpiouk, Frederic Bourgeois, Salavat R. Aglyamov, Adela Ben-Yakar, Stanislav Y. Emelianov

Author Affiliations +

Proceedings Volume 6435, Optical Interactions with Tissue and Cells XVIII; 64350P (2007) https://doi.org/10.1117/12.701874
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

An ultrasound-based method to detect and characterize the laser-induced microbubbles was developed. This method is based on temporal measurement of passive acoustic emission from cavity during laser-tissue interaction and simultaneous active pulse-echo ultrasound probing of the cavitation bubble. These measurements were used to estimate the location of the nanosecond laser induced cavity and to monitor the spatial and temporal behavior of the microbubble. The measurements agreed with estimates derived from a well-known Rayleigh model of the cavity collapse. Overall, the studies indicate that the developed ultrasound technique can be used to detect and accurately measure laser-induced microbubbles in tissue.

Citation Download Citation

Andrei B. Karpiouk, Frederic Bourgeois, Salavat R. Aglyamov, Adela Ben-Yakar, and Stanislav Y. Emelianov "Development of ultrasound technique to detect and characterize laser-induced microbubbles", Proc. SPIE 6435, Optical Interactions with Tissue and Cells XVIII, 64350P (6 February 2007); https://doi.org/10.1117/12.701874

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