Impact of magnification of imaging system on laser speckle contrast imaging

Jianjun Qiu; Hongyan Zhang; Pengcheng Li; Qingming Luo

doi:10.1117/12.823356

6 March 2009 Impact of magnification of imaging system on laser speckle contrast imaging

Jianjun Qiu, Hongyan Zhang, Pengcheng Li, Qingming Luo

Proceedings Volume 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine; 72800Z (2009) https://doi.org/10.1117/12.823356
Event: Photonics and Optoelectronics Meetings, 2008, Wuhan, China

Abstract

Laser Speckle Contrast Imaging (LSCI) is becoming a promising optical technique that generates two-dimensional map of blood flow of biological tissues in vivo with high spatiotemporal resolution. Experimental considerations for effective implementation of this technique have been extensively discussed. However, the influence of magnification of imaging system on laser speckle contrast imaging has not been sufficiently studied. In this study, we employ a porcelain plate model experiment to investigate the impact of magnification on statistical characteristic of speckle pattern and on the sensitivity of the measurement. We show that dynamic speckle contrast decreases with increasing magnification while static speckle contrast keeps constant with that. The sensitivity of LSCI has insignificant change throughout the magnifications in our experiments. Our results suggest that dynamic scattering areas with very slow speeds can be discriminated from the static ones, such as discriminating some small vessels from the cortex in cerebral blood flow imaging more efficiently when larger magnification is used.

Citation Download Citation

Jianjun Qiu, Hongyan Zhang, Pengcheng Li, and Qingming Luo "Impact of magnification of imaging system on laser speckle contrast imaging", Proc. SPIE 7280, Seventh International Conference on Photonics and Imaging in Biology and Medicine, 72800Z (6 March 2009); https://doi.org/10.1117/12.823356

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