Ultra-sensitive label-free biosensing by using single-mode coupled microcavity laser

Lei Xu; Hao Li; Xiang Wu; Lei Shang; Liying Liu

doi:10.1117/12.853331

28 April 2010 Ultra-sensitive label-free biosensing by using single-mode coupled microcavity laser

Lei Xu, Hao Li, Xiang Wu, Lei Shang, Liying Liu

Proceedings Volume 7682, Photonic Microdevices/Microstructures for Sensing II; 76820C (2010) https://doi.org/10.1117/12.853331
Event: SPIE Defense, Security, and Sensing, 2010, Orlando, Florida, United States

Abstract

We report that by using a single mode coupled microcavity laser, we successfully realized a sensitivity of 80 pg/ml for detecting BSA. The detecting scheme also works for other bio samples. The result proves that active sensing with microcavity laser can achieve ultrahigh sensitivity. Further analysis shows that the ultra-sensitivity comes from the slight change of coupling coefficient between the two coupled microcavities.

Citation Download Citation

Lei Xu, Hao Li, Xiang Wu, Lei Shang, and Liying Liu "Ultra-sensitive label-free biosensing by using single-mode coupled microcavity laser", Proc. SPIE 7682, Photonic Microdevices/Microstructures for Sensing II, 76820C (28 April 2010); https://doi.org/10.1117/12.853331

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