Detection of swine-origin influenza A (H1N1) viruses using a paired surface plasma waves biosensor

Li-Chen Su; Ying-Feng Chang; Ying-Chang Li; Jo-Ping Hsieh; Cheng-Chung Lee; Chien Chou

doi:10.1117/12.863622

19 August 2010 Detection of swine-origin influenza A (H1N1) viruses using a paired surface plasma waves biosensor

Li-Chen Su, Ying-Feng Chang, Ying-Chang Li, Jo-Ping Hsieh, Cheng-Chung Lee, Chien Chou

Proceedings Volume 7759, Biosensing III; 775905 (2010) https://doi.org/10.1117/12.863622
Event: SPIE NanoScience + Engineering, 2010, San Diego, California, United States

Abstract

In order to enhance the sensitivity of conventional rapid test technique for the detection of swine-origin influenza A (H1N1) viruses (S-OIVs), we used a paired surface plasma waves biosensor (PSPWB) based on SPR in conjunction with an optical heterodyne technique. Experimentally, PSPWB showed a 125-fold improvement at least in the S-OIV detection as compared to conventional enzyme linked immunosorbent assay. Moreover, the detection limit of the PSPWB for the S-OIV detection was enhanced 250-fold in buffer at least in comparison with that of conventional rapid influenza diagnostic test.

Citation Download Citation

Li-Chen Su, Ying-Feng Chang, Ying-Chang Li, Jo-Ping Hsieh, Cheng-Chung Lee, and Chien Chou "Detection of swine-origin influenza A (H1N1) viruses using a paired surface plasma waves biosensor", Proc. SPIE 7759, Biosensing III, 775905 (19 August 2010); https://doi.org/10.1117/12.863622

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