Paper
1 April 2015 Smart guidewires for smooth navigation in neurovascular intervention
Yanfei Chen, Matthew M. Barry, Mahdis Shayan, Brian T. Jankowitz, Xinjie Duan, Anne M. Robertson, Minking K. Chyu, Youngjae Chun
Author Affiliations +
Abstract
A smart guidewire using nitinol materials was designed, manufactured and evaluated the device functionality, such as bending performance, trackability, thermal effects, and thrombogenic response. Two types of nitinol material were partially used to enhance the guidewire trackability. A proposed smart guidewire system uses either one- or two-way shape-memory alloy nitinol (1W-SMA, 2W-SMA) wires (0.015, 381µm nitinol wire). Bending stiffness was measured using in vitro test system, which contains the NI USB-9162 data logger and LabView Signal Express 2010. Temperature distribution and displacement were evaluated via recording a 60Hz movie using a SC325 camera. Hemocompatibility was evaluated by scanning electron microscopy after one heating cycle of nitinol under the Na-citrate porcine whole blood circulation. A smart guidewire showed 30 degrees bending after applying or disconnecting electrical current. While the temperature of the nitinol wires increased more than 70 °C, the surrounding temperature with the commercially available catheter coverings showed below human body temperature showing 30 ̴ 33 °C. There was no significant platelet attachment or blood coagulation when the guidewire operates. Novel smart guidewires have been developed using shape memory alloy nitinol, which may represent a novel alternative to typical commercially available guidewires for interventional procedures.
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Yanfei Chen, Matthew M. Barry, Mahdis Shayan, Brian T. Jankowitz, Xinjie Duan, Anne M. Robertson, Minking K. Chyu, and Youngjae Chun "Smart guidewires for smooth navigation in neurovascular intervention", Proc. SPIE 9433, Industrial and Commercial Applications of Smart Structures Technologies 2015, 94330Y (1 April 2015); https://doi.org/10.1117/12.2084261
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KEYWORDS
Blood

In vitro testing

Body temperature

Blood vessels

Scanning electron microscopy

Manufacturing

Design for manufacturability

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