Widefield imaging of deep and superficial hemodynamics during an arterial vascular occlusion of the volar forearm

Gordon T. Kennedy; Rebecca Rowland; Amaan Mazhar; David J. Cuccia; Anthony J. Durkin

doi:10.1117/12.2610540

7 March 2022 Widefield imaging of deep and superficial hemodynamics during an arterial vascular occlusion of the volar forearm

Gordon T. Kennedy, Rebecca Rowland, Amaan Mazhar, David J. Cuccia, Anthony J. Durkin

Author Affiliations +

Proceedings Volume PC11934, Photonics in Dermatology and Plastic Surgery 2022; PC1193401 (2022) https://doi.org/10.1117/12.2610540
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Widefield spatial frequency domain imaging of tissue oxygen saturation (StO2), superficial (HbT1) and deep (HbT2) hemoglobin concentrations was performed on an arterial-venous insufficiency created by a forearm vascular occlusion test in 15 healthy subjects. Measured StO2 and HbT2 were significantly higher for regions of interest having underlying vessels compared to those without (microvasclature) at each time point (p < 0.01). During occlusion, the decrease in StO2 was greater for microvascular regions. These spatially resolved measurements suggest that image-based analysis is important as probe measurements can be confounded by probe location on the heterogeneous tissue.

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Gordon T. Kennedy, Rebecca Rowland, Amaan Mazhar, David J. Cuccia, and Anthony J. Durkin "Widefield imaging of deep and superficial hemodynamics during an arterial vascular occlusion of the volar forearm", Proc. SPIE PC11934, Photonics in Dermatology and Plastic Surgery 2022, PC1193401 (7 March 2022); https://doi.org/10.1117/12.2610540

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KEYWORDS

Hemodynamics

Near infrared spectroscopy

Tissues

Data acquisition

Image analysis

Ischemia

Oxygen

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