In vivo study of skin photodamage induced by a picosecond laser with a portable ultrahigh-resolution optical coherence tomography

Yin-Shen Cheng; Tai-Ang Wang; Hsiang-Chieh Lee; Chau Yee Ng; Meng-Tsan Tsai

doi:10.1117/12.2649521

17 March 2023 In vivo study of skin photodamage induced by a picosecond laser with a portable ultrahigh-resolution optical coherence tomography

Yin-Shen Cheng, Tai-Ang Wang, Hsiang-Chieh Lee, Chau Yee Ng, Meng-Tsan Tsai

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Proceedings Volume PC12352, Photonics in Dermatology and Plastic Surgery 2023; PC123520E (2023) https://doi.org/10.1117/12.2649521
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

In this study, a portable and ultrahigh-resolution OCT (UHR-OCT) system is developed, and the axial and transverse resolutions are approximately 2 and 5 m, respectively. Although picosecond lasers are widely used for clinical treatment, it is difficult to predict and observe the treatment outcome. The developed UHR-OCT system is implemented to observe the photodamage induced by the picosecond laser and the laser-induced optical breakdown (LIOB) can be observed. Furthermore, the recovery process is studied and compared by UHR-OCT. The results indicate that the UHR-OCT system can clearly identify the skin structures, and the induced photodamage can be quantitatively evaluated.

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Yin-Shen Cheng, Tai-Ang Wang, Hsiang-Chieh Lee, Chau Yee Ng, and Meng-Tsan Tsai "In vivo study of skin photodamage induced by a picosecond laser with a portable ultrahigh-resolution optical coherence tomography", Proc. SPIE PC12352, Photonics in Dermatology and Plastic Surgery 2023, PC123520E (17 March 2023); https://doi.org/10.1117/12.2649521

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KEYWORDS

Optical coherence tomography

Picosecond phenomena

Skin

In vivo imaging

Imaging systems

Laser optics

Light sources

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