Presentation
17 March 2023 Wide-field 400-khz polarization diversity optical coherence tomography imaging of retinal pigment epithelium melanin loss in retinitis pigmentosa
Author Affiliations +
Proceedings Volume PC12360, Ophthalmic Technologies XXXIII; PC1236013 (2023) https://doi.org/10.1117/12.2650439
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Our research investigates retinal pigmentary abnormalities in retinitis pigmentosa (RP) patients using a wide-field high-speed polarization diversity optical coherence tomography (PD-OCT) in a clinical setting. To account for the retinal curvature in the wide field-of-view, adaptive kernel-based spatial averaging is employed for degree-of-polarization-uniformity (DOPU) contrast formation with two complex OCT signals from two orthogonal polarization channels. In 7 patients diagnosed with RP, retinal pigment epithelium (RPE) melanin loss centered at the macula is compared to standard multimodal imaging techniques, including intensity-based OCT, fundus photography, and short-wavelength fundus autofluorescence images.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Yusi Miao, Khaldon Abbas, Destiny Hsu, Jun Song, Hoyoung Jung, Eduardo V. Navajas, and Myeong Jin Jin "Wide-field 400-khz polarization diversity optical coherence tomography imaging of retinal pigment epithelium melanin loss in retinitis pigmentosa", Proc. SPIE PC12360, Ophthalmic Technologies XXXIII, PC1236013 (17 March 2023); https://doi.org/10.1117/12.2650439
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KEYWORDS
Coherence imaging

Optical coherence tomography

Polarization

Optical imaging

Retinal scanning

Photography

Prototyping

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