Presentation
9 March 2023 Deep learning based on co-registered ultrasound and photoacoustic imaging improves assessment of rectal cancer chemoradiotherapy response
Author Affiliations +
Abstract
We present results of rectal cancer treatment response assessment using co-registered ultrasound and photoacoustic imaging from over 20 in vivo patients. We develop a deep learning model based on co-registered dual-modality images with individualized prior information. Compared to models using only ultrasound images, our model identifies complete treatment responders with significantly higher accuracy. We achieve a 3-class classification accuracy (normal, cancer, and image artifact) of 89.1±0.8%. To facilitate surgeons’ decision-making, we generate localized hotspots to indicate suspicious cancer regions based on model predictions. We conclude that the addition of photoacoustic imaging to conventional ultrasound improves treatment response assessment.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Yixiao Lin, Sitai Kou, Haolin Nie, and Quing Zhu "Deep learning based on co-registered ultrasound and photoacoustic imaging improves assessment of rectal cancer chemoradiotherapy response", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123790C (9 March 2023); https://doi.org/10.1117/12.2649328
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KEYWORDS
Cancer

Ultrasonography

Photoacoustic imaging

Tumor growth modeling

Photoacoustic spectroscopy

CRTs

Surgery

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