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We present the development of a multimodal photoacoustic and ultrasound imaging arrangement to investigate various conditioned pig livers during ex-vivo machine perfusion. Light and acoustic wave propagation simulation were performed with realistic optical and acoustical organ properties. Based on the simulation results, an optimized photoacoustic excitation and detection schemes were developed. Since the temperature of used perfusion liquids can be controlled, also temperature inhomogeneities were considered in the simulation. Preliminary experiments were performed with two single element detectors and a 2D-PA/US linear array probe.
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Robert Nuster, Bettina Leber, Guenther Paltauf, Philipp Stiegler, "Multimodal photoacoustic and ultrasound imaging of organs during ex-vivo
machine perfusion," Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123792E (27 March 2023); https://doi.org/10.1117/12.2655452