Engineered inorganic nanomaterials for biomedical and biosensing applications

Mélanie Romain; Amira Mahmoud; Julien Boudon; Rafik Ben Chaabane; Wilfrid Boireau; Nadine Millot

doi:10.1117/12.2648338

1 May 2023 Engineered inorganic nanomaterials for biomedical and biosensing applications

Mélanie Romain, Amira Mahmoud, Julien Boudon, Rafik Ben Chaabane, Wilfrid Boireau, Nadine Millot

Proceedings Volume PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII; PC123950J (2023) https://doi.org/10.1117/12.2648338
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

This communication addresses new inputs in the field of biosensing, diagnosis and theranostics by using engineered inorganic nanomaterials. We explore the use of gold nanoparticles (AuNPs), SuperParamagnetic Iron Oxide nanoparticles (SPIONs) and SPIONs decorated with AuNPs as new sensing nanoplatforms for cysteine. Another application concerns the targeting of extracellular vesicles. AuNPs are functionalized according to the biomarkers of interest. Raman, UV-Vis, XPS, DLS, zeta potential measurements, combined with SPR and TEM observations highlight grafting and colloidal stability at each step of the synthesis. Developments based on SPIONs as well as titanate nanotubes, as nanotheranostics tools, are also briefly presented.

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Citation Download Citation

Mélanie Romain, Amira Mahmoud, Julien Boudon, Rafik Ben Chaabane, Wilfrid Boireau, and Nadine Millot "Engineered inorganic nanomaterials for biomedical and biosensing applications", Proc. SPIE PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII, PC123950J (1 May 2023); https://doi.org/10.1117/12.2648338

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