Design, synthesis and characterization of copolymerized silica nanoparticle optical probes (Conference Presentation)

Gabor Patonay; Maged Henary

doi:10.1117/12.2654671

17 March 2023 Design, synthesis and characterization of copolymerized silica nanoparticle optical probes (Conference Presentation)

Gabor Patonay, Maged Henary

Author Affiliations +

Proceedings Volume PC12398, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XIV; PC1239806 (2023) https://doi.org/10.1117/12.2654671
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Silica nanoparticle optical probe properties are ultimately determined by the modified TEOS physical and chemical properties. This presentation will discuss the virtually unlimited possibilities of changing surface and internal properties of silica nanoparticles made of modified TEOS molecules. The resulting probe behavior is only limited by the chemical properties of modified TEOS and the proximity of the modified TEOS molecules in the nanoparticles which is determined by the concentration of the modified TEOS and the size of the nanoparticle. Silica nanoparticles are one of the few nanodevices that allow such a large variability. Any known optically active molecules that can covalently be attached to modified TEOS can be used to design these probes. Typical applications of these particles are for immunochemistry, flow cytometry, CE, forensic applications and other optical probe applications will be presented.

Conference Presentation

Citation Download Citation

Gabor Patonay and Maged Henary "Design, synthesis and characterization of copolymerized silica nanoparticle optical probes (Conference Presentation)", Proc. SPIE PC12398, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XIV, PC1239806 (17 March 2023); https://doi.org/10.1117/12.2654671

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