Broadband characterization of the retinal tissue response to flickering light through optoretinography implemented with the spatio-temporal optical coherence tomography (STOC-T)

Piotr F. Wegrzyn; Sławomir Tomczewski; Dawid Borycki; Kamil Liżewski; Andrea Curatolo; Maciej Wojtkowski

doi:10.1117/12.3005721

13 March 2024 Broadband characterization of the retinal tissue response to flickering light through optoretinography implemented with the spatio-temporal optical coherence tomography (STOC-T)

Piotr F. Wegrzyn, Sławomir Tomczewski, Dawid Borycki, Kamil Liżewski, Andrea Curatolo, Maciej Wojtkowski

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Proceedings Volume PC12824, Ophthalmic Technologies XXXIV; PC128240M (2024) https://doi.org/10.1117/12.3005721
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

We report Spatio-Temporal Optical Coherence Tomography (STOC-T) for acquiring optoretinography-based comprehensive characterization of retinal tissue response to flickering light across a broad spectrum (5Hz to 45Hz). This approach involves the introduction of frequency chirp during stimulation, offering a more practical means of assessing the frequency traits of photoreceptors. Our technique unveiled notable variations in response amplitudes between two subjects, both in the context of diverse stimulus amplitudes and when comparing responses to both rectangular and sinusoidal stimuli. This innovative method establishes a path for the unbiased identification of temporal-contrast sensitivity functions, exclusively focused on photoreceptors.

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Piotr F. Wegrzyn, Sławomir Tomczewski, Dawid Borycki, Kamil Liżewski, Andrea Curatolo, and Maciej Wojtkowski "Broadband characterization of the retinal tissue response to flickering light through optoretinography implemented with the spatio-temporal optical coherence tomography (STOC-T)", Proc. SPIE PC12824, Ophthalmic Technologies XXXIV, PC128240M (13 March 2024); https://doi.org/10.1117/12.3005721

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KEYWORDS

Optical coherence tomography

Tissues

Data acquisition

Electrophysiological tests

Visualization

Photography

Retina

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