CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12830 > Article
Presentation
13 March 2024 Validation of total hemoglobin concentrations in healthy human subjects by visible-light spectroscopic optical coherence tomography
Carlos Cuartas-Vélez, Isabella Gómez Gallego, Nienke Bosschaart
Author Affiliations +
Proceedings Volume PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII; PC128301V (2024) https://doi.org/10.1117/12.3001549
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Quantification of total hemoglobin concentrations [tHb] is imperative to determine blood-related diseases such as anemia. In this work, we validate [tHb] estimates by visible-light spectroscopic optical coherence tomography (vis-sOCT) with the gold standard, intravenous blood sample analysis from a commercial avoximeter. We recruited a group of 27 volunteers and retrieved [tHb] with vis-sOCT data from the microcirculation in the skin of the left posterior forearm. Expected [tHb] were obtained from blood sample analysis by a commercial analyzer. We compare the [tHb] estimated by vis-sOCT with the expected [tHb]. Additionally, the effect of multiple factors of influence such as gender, skin tone, and epidermal thickness is investigated.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Carlos Cuartas-Vélez, Isabella Gómez Gallego, and Nienke Bosschaart "Validation of total hemoglobin concentrations in healthy human subjects by visible-light spectroscopic optical coherence tomography", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC128301V (13 March 2024); https://doi.org/10.1117/12.3001549
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Optical coherence tomography
Optical spectroscopy
Spectroscopy
Human subjects
Statistical analysis
Biological samples
Blood
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top