Optical coherence tomography as a tool for interrogating pathologies of the tympanic membrane and middle ear

Marcela Moran; Zihan Yang; Wihan Kim; Ryan Long; John S. Oghalai; Brian E. Applegate

doi:10.1117/12.3017301

19 June 2024 Optical coherence tomography as a tool for interrogating pathologies of the tympanic membrane and middle ear

Marcela Moran, Zihan Yang, Wihan Kim, Ryan Long, John S. Oghalai, Brian E. Applegate

Author Affiliations +

Proceedings Volume PC13009, Clinical Biophotonics III; PC1300904 (2024) https://doi.org/10.1117/12.3017301
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Abstract

We have been investigating Optical Coherence Tomography (OCT) as a tool to measure the tympanic membrane and middle ear morphology and vibrational response. The hand-held OCT ostoscope system, based on a 1.3 µm swept laser, is integrated into an endoscopy cart. It has an ~ 8 mm diameter field of view, 38 µm lateral resolution, 35 µm axial resolution, A-line rate of 200 kHz, and subnanometer sensitivity to vibration within the tympanic membrane and middle ear. The system has been used in the clinic at USC Keck Medical Center to image over 100 patients and healthy volunteers. Total imaging time is ~2 minutes, which allows it to easily fit into the clinic workflow, while providing high-resolution images and vibrometric assessment of the tympanic membrane and middle ear. The functional and morphological features visible within these image sets that allow us to readily differentiate among pathologies, will be discussed.

Conference Presentation

Citation Download Citation

Marcela Moran, Zihan Yang, Wihan Kim, Ryan Long, John S. Oghalai, and Brian E. Applegate "Optical coherence tomography as a tool for interrogating pathologies of the tympanic membrane and middle ear", Proc. SPIE PC13009, Clinical Biophotonics III, PC1300904 (19 June 2024); https://doi.org/10.1117/12.3017301

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