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1 November 2005 Measurement of burn depths in rats using multiwavelength photoacoustic depth profiling
Mutsuo Yamazaki, Shunichi Sato, Hiroshi Ashida, Daizo Saito, Yoshiaki Okada, Minoru Obara
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Journal of Biomedical Optics, Vol. 10, Issue 6, 064011 (November 2005). https://doi.org/10.1117/1.2137287
Abstract
We perform measurement of photoacoustic (PA) signals for burned skin in rats in the spectral range of 500 to 650 nm. The wavelength dependence of PA signal amplitude shows characteristics similar to those of the absorption spectrum of hemoglobin, suggesting that the PA signal originates from blood in the uninjured skin tissue under the injured tissue layer. High-contrast signals are obtained in the spectral range of 532 to 580 nm. At 550 nm, a PA detector is scanned on the wounds and PA tomograms are obtained. The tomograms clearly show the zones of stasis, demonstrating that a 2-D PA measurement is useful for burn depth assessment.
©(2005) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Mutsuo Yamazaki, Shunichi Sato, Hiroshi Ashida, Daizo Saito, Yoshiaki Okada, and Minoru Obara "Measurement of burn depths in rats using multiwavelength photoacoustic depth profiling," Journal of Biomedical Optics 10(6), 064011 (1 November 2005). https://doi.org/10.1117/1.2137287
Published: 1 November 2005
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Cited by 46 scholarly publications and 1 patent.
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KEYWORDS
Skin
Tissues
Blood
Absorption
Tissue optics
Photoacoustic spectroscopy
Blood vessels
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