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25 April 2017 Photoacoustic imaging probe for detecting lymph nodes and spreading of cancer at various depths
Yong-Jae Lee, Eun-Ju Jeong, Hyun-Woo Song, Chang-Geun Ahn, Hyung Wook Noh, Joo Yong Sim, Dong Hoon Song, Min Yong Jeon, Susung Lee, Heewon Kim, Meihua Zhang, Bong Kyu Kim
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Journal of Biomedical Optics, Vol. 22, Issue 9, 091513 (April 2017). https://doi.org/10.1117/1.JBO.22.9.091513
Abstract
We propose a compact and easy to use photoacoustic imaging (PAI) probe structure using a single strand of optical fiber and a beam combiner doubly reflecting acoustic waves for convenient detection of lymph nodes and cancers. Conventional PAI probes have difficulty detecting lymph nodes just beneath the skin or simultaneously investigating lymph nodes located in shallow as well as deep regions from skin without any supplementary material because the light and acoustic beams are intersecting obliquely in the probe. To overcome the limitations and improve their convenience, we propose a probe structure in which the illuminated light beam axis coincides with the axis of the ultrasound. The developed PAI probe was able to simultaneously achieve a wide range of images positioned from shallow to deep regions without the use of any supplementary material. Moreover, the proposed probe had low transmission losses for the light and acoustic beams. Therefore, the proposed PAI probe will be useful to easily detect lymph nodes and cancers in real clinical fields.
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE) 1083-3668/2017/$25.00 © 2017 SPIE
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Yong-Jae Lee, Eun-Ju Jeong, Hyun-Woo Song, Chang-Geun Ahn, Hyung Wook Noh, Joo Yong Sim, Dong Hoon Song, Min Yong Jeon, Susung Lee, Heewon Kim, Meihua Zhang, and Bong Kyu Kim "Photoacoustic imaging probe for detecting lymph nodes and spreading of cancer at various depths," Journal of Biomedical Optics 22(9), 091513 (25 April 2017). https://doi.org/10.1117/1.JBO.22.9.091513
Received: 2 December 2016; Accepted: 5 April 2017; Published: 25 April 2017
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Cited by 17 scholarly publications.
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KEYWORDS
Lymphatic system
Ultrasonography
Optical fibers
Skin
Acoustics
Photoacoustic imaging
Cancer
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