Preliminary investigation into the analytical potential of a multiwavelength fiber drop analyzer with special reference to applications in medical diagnostics

Norman Douglas McMillan; Eon O'Mongain; James Edward Walsh; Liam Breen; Duncan McMillan; Michael J. Power; John P. O'Dea; Seamus M. Kinsella; Mairead P. Kelly; Conor Hammil; Dermot Orr

doi:10.1117/12.184442

1 December 1994 Preliminary investigation into the analytical potential of a multiwavelength fiber drop analyzer with special reference to applications in medical diagnostics

Norman Douglas McMillan, Eon O'Mongain, James Edward Walsh, Liam Breen, Duncan McMillan, Michael J. Power, John P. O'Dea, Seamus M. Kinsella, Mairead P. Kelly, Conor Hammil, Dermot Orr

Author Affiliations +

Optical Engineering, Vol. 33, Issue 12, (December 1994). https://doi.org/10.1117/12.184442

Abstract

A preliminary investigation into the use of multiwavelength fiber drop analyzer (FDA) for the measurement of viscosity, spectral absorbance, and refractive index is made with a view to obtaining conservative estimates of the instrumental capability of the FDA for these measurands. Some important new insights into drop vibrations are made from studies on the fiber drop traces (FDTs) of mechanically excited damped vibrations in drops with a set volume. A brief description of the feasibility measurements on the first application of the FDA in the diagnosis of disease in synovial fluid is given. Strong experimental evidence is reported for the existence of the surface-guided wave (SGW) peak of the fiber drop trace and some new insights into the nature of the FDT are suggested based on a comparative study of the FDTs from a multiple-wavelength and a single-wavelength FDA. The earlier reported drop period dependence on applied electric field is critically reexamined, a new interpretation of this effect is suggested, and an experimental study of clarification is given. Finally, a brief review of the projected capabilities of the FDA based on the work reported here is provided.

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Norman Douglas McMillan, Eon O'Mongain, James Edward Walsh, Liam Breen, Duncan McMillan, Michael J. Power, John P. O'Dea, Seamus M. Kinsella, Mairead P. Kelly, Conor Hammil, and Dermot Orr "Preliminary investigation into the analytical potential of a multiwavelength fiber drop analyzer with special reference to applications in medical diagnostics," Optical Engineering 33(12), (1 December 1994). https://doi.org/10.1117/12.184442

Published: 1 December 1994

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