We introduced an improved iteration of a panoramic retinal (panretinal) handheld swept-source OCT angiography (OCTA) imaging system with an 800kHz VCSEL light source. The advanced system successfully achieved a remarkable 140° field of view (FOV, visual angle measured from the pupil plane), enabling comprehensive imaging coverage from the posterior pole to the peripheral retina in a single capture.
We demonstrated a contact handheld ultra-widefield (UWF) swept-source OCT (SS-OCT) imaging system with a 400 kHz VCSEL light source that achieved an unprecedented 140° field of view (FOV), which was capable to extend the imaging area from the posterior pole to peripheral retina in a single shot. The contact imaging approach provided faster and more efficient retinal imaging and improve image quality. To the best of our knowledge, this prototype achieved the widest FOV among all the retinal OCT research prototypes and commercial systems in desktop and portable format.
Uveal melanoma is the most common intraocular cancer in adults and may cause vision loss as well as death due to distant metastases. Early detection of tumors is critical for vision preservation and may reduce mortality. Many patients with uveal melanoma do not develop symptoms in early stages of disease when tumors are small. Diagnosis requires examination of the eye using specialized equipment and may require advanced imaging techniques. Here, we studied the electrical properties of eyes to investigate a novel, easy-to-use method for detecting uveal melanoma. We used finite element analysis to study the electrical impedance and current density in bovine eyes. We also measured the impedance and current flow in the preserved bovine eyes using a high precision impedance analyzer. Our experimental data show that a 6 mm-diameter added tissue was detected inside a 30-mm diameter eyeball by impedance analyzer, paving the way toward detection of solid tumors in eyeballs.
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