Prof. Beate Röder Profile

Prof. Beate Röder

Prof.Dr. at Humboldt-Univ zu Berlin

SPIE Involvement:

Author

Publications (22)

SPIE Journal Paper | 5 November 2013 Open Access

Luminescence investigation of photosensitizer distribution in skin: correlation of singlet oxygen kinetics with the microarchitecture of the epidermis

Jan Schlothauer, Julian Falckenhayn, Tobias Perna, Steffen Hackbarth, Beate Röder

JBO, Vol. 18, Issue 11, 115001, (November 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.11.115001

KEYWORDS: Luminescence, Skin, Picosecond phenomena, Oxygen, Photodynamic therapy, Ear, In vivo imaging, Tissue optics, Environmental sensing, Near infrared

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Proceedings Article | 13 March 2013 Paper

LEDs as excitation source for time resolved singlet oxygen luminescence detection in cell suspensions

Steffen Hackbarth, Annegret Preuss, Tobias Perna, Jan Schlothauer, Beate Röder

Proceedings Volume 8568, 85680W (2013) https://doi.org/10.1117/12.2008185

KEYWORDS: Light emitting diodes, Oxygen, Luminescence, Signal detection, Absorption, Visible radiation, Diffusion, Photodynamic therapy, Photon counting, Electroluminescent displays

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SPIE Journal Paper | 8 November 2012 Open Access

Time-resolved singlet oxygen luminescence detection under photodynamic therapy relevant conditions: comparison of ex vivo application of two photosensitizer formulations

Jan Schlothauer, Steffen Hackbarth, Lutz Jäger, Kai Drobniewski, Hemantbhai Patel, Sergiu Gorun, Beate Röder

JBO, Vol. 17, Issue 11, 115005, (November 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.11.115005

KEYWORDS: Luminescence, Oxygen, Picosecond phenomena, Skin, Photodynamic therapy, Ear, Microscopy, In vivo imaging, Diffusion, Phosphorescence

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Proceedings Article | 3 March 2010 Paper

In vivo detection of time-resolved singlet oxygen luminescence under PDT relevant conditions

Jan Schlothauer, Beate Röder, Steffen Hackbarth, Jürgen Lademann

Proceedings Volume 7551, 755106 (2010) https://doi.org/10.1117/12.839851

KEYWORDS: Oxygen, Luminescence, Skin, Picosecond phenomena, In vivo imaging, Photodynamic therapy, Photolysis, Signal processing, Diffusion, Quantum efficiency

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Proceedings Article | 14 July 2009 Paper

Synthesis and cellular localization of porphyrinic pigments

Sarah Sareh, Sarah Kong, Lenin Parrales, Anna Jung, Kara Cross, Beate Röder, Meden Isaac, Ursula Simonis

Proceedings Volume 7380, 73804R (2009) https://doi.org/10.1117/12.823023

KEYWORDS: Content addressable memory, Cell death, Magnesium, Cancer, Photodynamic therapy, Chromatography, Prostate cancer, Luminescence, NOx, Picosecond phenomena

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Proceedings Article | 13 July 2009 Paper

Singlet oxygen kinetics inside living cells: observation of endogenous quencher consumption and consequences for the spatial resolution in time-resolved measurements

Steffen Hackbarth, Jan Schlothauer, Annegret Preuß, Beate Röder

Proceedings Volume 7380, 738045 (2009) https://doi.org/10.1117/12.822830

KEYWORDS: Oxygen, Picosecond phenomena, Luminescence, Electroluminescent displays, Molecules, Spatial resolution, Quenching (fluorescence), Diffusion, Photodynamic therapy, Photon counting

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Proceedings Article | 10 September 2008 Paper

Observation of polymer degradation processes in photovoltaic modules via luminescence detection

B. Röder, E. Ermilov, D. Philipp, M. Köhl

Proceedings Volume 7048, 70480F (2008) https://doi.org/10.1117/12.793795

KEYWORDS: Luminescence, Polymers, Solar cells, Ultraviolet radiation, Photovoltaic detectors, Scattering, Light scattering, Photovoltaics, Nondestructive evaluation, Crystals

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Proceedings Article | 2 September 2008 Paper

Novel cycloketo tetraphenylporphyrins: spectroscopic study of structure-properties relationships

Eugeny Ermilov, Stefan Jasinski, Norbert Jux, Beate Röder

Proceedings Volume 7049, 704905 (2008) https://doi.org/10.1117/12.793356

KEYWORDS: Luminescence, Absorption, Oxygen, Chemical species, Quantum efficiency, Spectroscopy, Photodynamic therapy, Hydrogen, Metals, Tumors

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Proceedings Article | 20 April 2006 Paper

Trap formation and energy transfer in pheophorbide a-DAB-dendrimers and pyropheophorbide a-fullerene C₆₀ hexaadduct molecular systems

Beate Röder, Eugeny Ermilov, Steffen Hackbarth, Matthias Helmreich, Norbert Jux

Proceedings Volume 6192, 61922O (2006) https://doi.org/10.1117/12.661908

KEYWORDS: Luminescence, Molecules, Quantum efficiency, Oxygen, Fullerenes, Dendrimers, Chromophores, Absorption, Energy transfer, Molecular energy transfer

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Proceedings Article | 29 December 1997 Paper

Pharmacokinetics evaluation of 132-hydroxy-bacteriopheophorbid-a methyl ester and octa-alpha-butyloxy-zinc phthalocyanine for future application in PDT

M. Samy Ismail, Cathrin Dressler, Beate Roeder, H. Weitzel, Hans-Peter Berlien

Proceedings Volume 3191, (1997) https://doi.org/10.1117/12.297821

KEYWORDS: Photodynamic therapy, Lung, Tissues, Absorption spectroscopy, Liver, Skin

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Proceedings Article | 31 January 1996 Paper

Synthesis of NIR-absorbing monofunctionalized pthalocyanines via copolymer coupling

Ralf Herter, Rainier Senz, Beate Roeder

Proceedings Volume 2625, (1996) https://doi.org/10.1117/12.230965

KEYWORDS: Photodynamic therapy, Polymers, Tissues, Cancer, Oxygen, Tumors, Absorption, Monoclonal antibodies, Mass attenuation coefficient, Silver

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Proceedings Article | 31 January 1996 Paper

Theoretical description of interactions between some tetrapyrroles and cyclodextrin dimers

Wolfgang Decker, Beate Roeder

Proceedings Volume 2625, (1996) https://doi.org/10.1117/12.230969

KEYWORDS: Molecules, Computer simulations, Algorithms, Forward looking infrared, Silver, Photodynamic therapy, Tissues, Cadmium sulfide, Monoclonal antibodies, Glucose

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Proceedings Article | 31 January 1996 Paper

Photophysical properties of pheophorbide-a in different carrier-systems

Beate Roeder, St. Hackbarth, Olaf Korth, Ralf Herter, Thomas Hanke, Wolfgang Hoehne

Proceedings Volume 2625, (1996) https://doi.org/10.1117/12.230959

KEYWORDS: Luminescence, Bioalcohols, Molecules, Oxygen, Photodynamic therapy, Picture Archiving and Communication System, Tissues, Absorption, Diffusion, Molecular interactions

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Proceedings Article | 1 March 1995 Paper

Absorption spectroscopic analysis of the pharmacokinetics of octa-alpha-butyloxy-zinc phthalocyanine in Lewis lung carcinoma-bearing mice

Cathrin Dressler, M. Samy Ismail, Simone Stroebele, Christian Nowak, Ralf Herter, Rainier Senz, Roland Hagemann, Peter Koeppe, Beate Roeder, Hans-Peter Berlien

Proceedings Volume 2371, (1995) https://doi.org/10.1117/12.203413

KEYWORDS: Lung, Absorption spectroscopy, Absorption, Spectroscopy, Metals, Ions, Plasma, Tissues, Molecules, Photodynamic therapy

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Proceedings Article | 1 March 1995 Paper

Syntheses, photophysical and first aspects of the photosensitizing properties of a new water-soluble SiPc

Silke Mueller, Dieter Woehrle, Maria Shopova, Beate Roeder, Maria Schoenermark

Proceedings Volume 2371, (1995) https://doi.org/10.1117/12.203412

KEYWORDS: Silicon, Oxygen, Quantum efficiency

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Proceedings Article | 12 January 1995 Paper

Pharmacokinetics of the far red absorbing octa-alpha-butyloxy-zinc phthalocyanine in Lewis lung carcinoma bearing mice

Cathrin Dressler, M. Samy Ismail, Christian Nowak, Ralf Herter, Rainier Senz, Roland Hagemann, Beate Roeder, Hans-Peter Berlien

Proceedings Volume 2325, (1995) https://doi.org/10.1117/12.199147

KEYWORDS: Tissues, Tumors, Lung, Photodynamic therapy, Cancer, Liver, Spleen, Skin, Absorption, Oxygen

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Proceedings Article | 12 January 1995 Paper

Time-resolved detection of singlet oxygen luminescence in red cell ghosts generated by photosensitizers via excitation in the far red

Stefan Oelckers, Thomas Hanke, Joerg Moser, Beate Roeder

Proceedings Volume 2325, (1995) https://doi.org/10.1117/12.199134

KEYWORDS: Luminescence, Phosphorescence, Photodynamic therapy, Oxygen, Molecules, Tumors, Signal detection, Laser therapeutics, Complex systems, Cancer

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Proceedings Article | 12 January 1995 Paper

Spectroscopic studies on Si-phthalocyanines and Si-naphthalocyanines

C. von Schoenermark, Andreas Volkmer, Silke Mueller, Dieter Woehrle, Beate Roeder

Proceedings Volume 2325, (1995) https://doi.org/10.1117/12.199164

KEYWORDS: Luminescence, Silicon, Bioalcohols, Polymers, Photodynamic therapy, Cancer, Oxygen, Absorption, Phosphorescence, Spectroscopy

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Proceedings Article | 12 January 1995 Paper

Photophysical characterization of far-red absorbing photosensitizers in cyclodextrin solutions

Beate Roeder, Carsten Zimmermann, Ralf Herter

Proceedings Volume 2325, (1995) https://doi.org/10.1117/12.199181

KEYWORDS: Molecules, Absorption, Photodynamic therapy, Luminescence, Oxygen, Cancer, Zinc, Kinematics, Absorbance, Bioalcohols

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Proceedings Article | 1 March 1994 Paper

Pharmakokinetics of 132-hydroxy-bacteriopheophorbide: a methyl ester studied by fluorescence spectroscopy on Lewis lung carcinoma bearing mice

Beate Roeder, Cathrin Dressler, B. Fuchs, Roland Hagemann, Hans-Peter Berlien, Christian Nowak, Joerg Moser

Proceedings Volume 2078, (1994) https://doi.org/10.1117/12.168685

KEYWORDS: Luminescence, Tumors, Fluorescence spectroscopy, Lung, Tissues, Blood, Signal detection, Skin, Kidney, Liver

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Proceedings Article | 17 June 1993 Paper

Photophysical properties of protein conjugates with PDT photosensitizers

Alexander Savitsky, K. Lopatin, Oleg Lobanov, N. Golubeva, Marina Poroshina, Elena Chernyaeva, L. Solovieva, Eugeny Lukyanets, Maria Galpern, B. Roder, Dirk Nather

Proceedings Volume 1922, (1993) https://doi.org/10.1117/12.146207

KEYWORDS: Luminescence, Proteins, Absorption, Molecules, Absorbance, Photodynamic therapy, Monoclonal antibodies, Sodium, Aluminum, Chlorine

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Photodynamic therapy (PDT) of malignant tumors is based on the property of some photosensitizers to be accumulated by tumour tissues'. On subsequent illumination with light of the wavelength absorbed by these photosensitizers tumour cells can be destroyed. Hematoporphyrin derivative and similar agents presently have some negative features. First, these agents do not possess optimal absorption spectrum. In particular the absorbance in the red region is not very high. Second, the composition of these agents varies for different preparations and with the storage time. Third, they do not possess a sufficient selectivity for malignant cells. Furthermore, they are also accumulated in skin causing its damage upon exposure to light. Thus at present the developing of the effective PDT photosensitizers is of great interest. Recently some of this interest has been focussed on the phthalocyanines (PC). These dyes have sufficient molar extinction coefficient (<10 M1cm1) in red region of optical spectrum (650 700 nm). They are non-toxic. Some of them are effective photosensitizers and produce singlet oxygen. They are relatively easy synthesized and resistant to chemical degradation. PC can have different groups added to the external macrocycle perifery. These groups mainly determine chemical properties and solubility. They offer possibility to bind the dyes to any other molecules, for example, proteins. The properties of naphthalocyanines (NC) are rather similar to the ones of PC, but the most efficient absorption band is in region of 750 - 800 nm. An important problem is to increase the ratio between the level of photosensitizer in malignant and normal tissues. One of the possible solutions is the use of photoimmunotoxins, i.e. conjugates of photosensitizers with monoclonal antibodies (mAb) against cancer antigens or tumor marker. Experiments with immunoglobulin-hematoporphyrin2 and dimetoxyhematoporphyrin3 as well as chiorin e6 conjugates4 showed that they retained both photochemical properties of free dyes and immunological ones of antibodies.

Proceedings Article | 1 November 1991 Paper

Characterization of photobiophysical properties of sensitizers used in photodynamic therapy

Beate Roeder, Dirk Nather

Proceedings Volume 1525, (1991) https://doi.org/10.1117/12.48194

KEYWORDS: Oxygen, Quantum efficiency, Molecules, Photodynamic therapy, Biomedical optics, Luminescence, Metals, Molecular lasers, Aluminum, Energy transfer

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Showing 5 of 22 publications

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